1.主持国家自然科学基金3项,江西省自然科学基金1项;参与完成省部级以上课题5项。 [1]主持国家自然科学基金:吴茱萸“陈旧者良”的科学内涵研究 [2]主持国家自然科学基金:基于色谱联用技术的开心散抗老年痴呆活性成分的筛选及作用机制研究 [3]主持完成国家自然科学基金:基于代谢组学的马兜铃蜜炙减毒的物质基础及机理研究 [4]参与(排名第二)完成新药创制重大专项:枳壳中抗老年痴呆有效成分的成药性研究 [5]主持完成省自然科学基金:基于色谱联用技术的葡萄内酯活性代谢产物的在线筛选 2.发表研究论文40多篇,SCI收录20多篇。 [1]Preparation of fluorine functionalized magneticnanoparticles for fast extraction and analysis ofperfluorinated compounds. Analytical Methods, 2015, 7: 9054-9063. [2]Cloud point extraction-HPLC method for the determinaton and pharmacokinetic study of aristolochic acids in rat plasma after oral administration of Aristolochiae Fructus. Journal of Chromatography B, 2014, 953-954(1): 73-79. [3]Acute and subacute toxicity of the extract of Aristolochiae fructus and honey-fried Aristolochiae Fructus in rodents. Biological and Pharmaceutical Bulletin, 2014, 37(3): 387-393. [4]Inhibitory effects of phenolic compounds from Artocarpus styracifolius on respiratory burst of rat neutrophils. Pharmaceutical Biology, 2014, 52(8): 944-950. [5]一测多评法测定马兜铃中4个马兜铃酸类成分含量,中药材,2014, 37(9): 1617-1620. [6]代谢组学在中药毒理学研究中的应用,中药新药与临床药理,2014, 25(5): 383-388. [7]蜜炙对马兜铃中马兜铃酸类物质含量的影响,中药材,2013, 36(4): 538-541. [8]An HPLC method for the determination of auraptene in dog plasma: application to pharmacokinetic study. Latin American Journal of Pharmacy, 2012, 31(2): 251-256.
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